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R&D

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Hormone Replacement Therapy (HRT)

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During menopause a woman’s body gradually produces less of the hormones estrogen and progesterone. Menopause is a normal change in a woman’s life and, in most cases, occurs between the ages of 45 and 55. However, in some women menopause starts at a younger age. Some of the reasons are associated with medical treatments such as surgery to remove the ovaries, family history (genes), or cancer treatments such as chemotherapy or radiation to the pelvic area.

Some women may not have any of the symptoms associated with menopause at all. Other women may suffer significantly from symptoms like hot flashes (waves of warm spells in the face, neck, or chest), night sweats or sleeping problems, vaginal dryness and thinning of bones, which may lead to loss of height and bone fractures.

 

Common Menopausal Symptoms

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Hair Loss/ Brittle Nails/ Itchy Skin

Irregular Periods

Hot Flashes

Vaginal Dryness/ Incontinence

Night Sweats/ Sleep Disorders/ Fatigue

Weight Gain/ Bloating/ Digestive Problems

Difficult Concentrating/ Memory Lapses/ Dizziness/ Irritability

Irregular Heartbeat

Loss of Libido

Osteoporosis

Mood Swings/ Depression/ Panic Disorder

Like all medicines, hormone therapy has risks and benefits. If a woman decides to use hormones, she should use the lowest effective dose. For treatment of menopausal symptoms, a health care provider should be consulted to discuss treatment options.

HRT is a system of medical treatment for menopausal (peri- and postmenopausal) women. It is a treatment that may prevent discomfort caused by diminished circulating estrogen and progesterone hormones. In case of surgically or prematurely induced menopause, HRT may prolong life and reduce incidence of dementia. The main types of hormones involved are estrogens, progesterone or progestins and, less commonly, testosterone.

 

Benefits from using hormones to treat menopause

What are the risks of using hormones?

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For some women, hormone therapy may increase the chances of blood clots, heart attacks, strokes, breast cancer and gall bladder disease. 

Estrogen increases the chance of developing endometrial cancer (cancer of the uterine lining).  Adding progestin to the estrogen regiment lowers this risk.

  • HRT is the most effective approach and the FDA has approved medicine for the relief of menopause symptoms such as hot flashes, night sweats or vaginal dryness

  • Hormones may reduce the chances of developing osteoporosis

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